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Did you mean skin and skin (955,915 results)?
The expression of SnoN in normal human skin and cutaneous keratinous neoplasms.
Zhang X, Egawa K, Xie Y, Ihn H. Zhang X, et al. Int J Dermatol. 2009 Jun;48(6):579-83. doi: 10.1111/j.1365-4632.2009.03685.x. Int J Dermatol. 2009. PMID: 19538364
This study investigated the expression and significance of SnoN protein in normal human skin and in the development of seborrheic keratosis (SK), basal cell carcinoma (BCC), and squamous cell carcinoma (SCC) of the skin. ...CONCLUSIONS: On the basis of our results, …
This study investigated the expression and significance of SnoN protein in normal human skin and in the development of seborrheic ker …
Chronic delayed-type hypersensitivity reaction as a means to treat alopecia areata.
Zöller M, Freyschmidt-Paul P, Vitacolonna M, McElwee KJ, Hummel S, Hoffmann R. Zöller M, et al. Clin Exp Immunol. 2004 Mar;135(3):398-408. doi: 10.1111/j.1365-2249.2003.02380.x. Clin Exp Immunol. 2004. PMID: 15008971 Free PMC article.
The acute phase of alopecia areata (AA) is characterized by an increase in CD44v3+ and CD44v10+ skin-infiltrating leucocytes (SkIL). Induction of a contact eczema, one of the therapeutic options in AA, can be mitigated strongly by a blockade of CD44v10. ...AA-affect …
The acute phase of alopecia areata (AA) is characterized by an increase in CD44v3+ and CD44v10+ skin-infiltrating leucocytes (SkIL …
Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients.
Aarntzen EH, Schreibelt G, Bol K, Lesterhuis WJ, Croockewit AJ, de Wilt JH, van Rossum MM, Blokx WA, Jacobs JF, Duiveman-de Boer T, Schuurhuis DH, Mus R, Thielemans K, de Vries IJ, Figdor CG, Punt CJ, Adema GJ. Aarntzen EH, et al. Clin Cancer Res. 2012 Oct 1;18(19):5460-70. doi: 10.1158/1078-0432.CCR-11-3368. Epub 2012 Aug 15. Clin Cancer Res. 2012. PMID: 22896657
Monocyte-derived DC, electroporated with mRNA encoding gp100 and tyrosinase, were pulsed with keyhole limpet hemocyanin and administered intranodally. TAA-specific T-cell responses were monitored in blood and skin-test infiltrating lymphocyte (SKIL) cultures. RESULT …
Monocyte-derived DC, electroporated with mRNA encoding gp100 and tyrosinase, were pulsed with keyhole limpet hemocyanin and administered int …
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination.
Aarntzen EH, De Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit A, Blokx WA, Van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG. Aarntzen EH, et al. Cancer Res. 2013 Jan 1;73(1):19-29. doi: 10.1158/0008-5472.CAN-12-1127. Epub 2012 Oct 18. Cancer Res. 2013. PMID: 23087058 Clinical Trial.
In 4 of 15 patients vaccinated with MHC-I/II-loaded DCs and 1 of 14 patients vaccinated with MHC-I-loaded DCs, we detected TAA-specific CD8(+) T cells with maintained IFN-gamma production in skin test infiltrating lymphocyte (SKIL) cultures and circulating TAA-speci …
In 4 of 15 patients vaccinated with MHC-I/II-loaded DCs and 1 of 14 patients vaccinated with MHC-I-loaded DCs, we detected TAA-specific CD8( …
Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients.
Bol KF, Figdor CG, Aarntzen EH, Welzen ME, van Rossum MM, Blokx WA, van de Rakt MW, Scharenborg NM, de Boer AJ, Pots JM, Olde Nordkamp MA, van Oorschot TG, Mus RD, Croockewit SA, Jacobs JF, Schuler G, Neyns B, Austyn JM, Punt CJ, Schreibelt G, de Vries IJ. Bol KF, et al. Oncoimmunology. 2015 Apr 1;4(8):e1019197. doi: 10.1080/2162402X.2015.1019197. eCollection 2015 Aug. Oncoimmunology. 2015. PMID: 26405571 Free PMC article.
A vaccination cycle consisting of three vaccinations with up to 1510(6) DC per vaccination at a biweekly interval, was repeated after 6 and 12 months in the absence of disease progression. mRNA-optimized DC were injected intranodally, because of low CCR7 expression on the DC, and …
A vaccination cycle consisting of three vaccinations with up to 1510(6) DC per vaccination at a biweekly interval, was repeated after 6 and …
[The expression of SnoN in human hypertrophic scar fibroblasts and the mechanism of its participation in hypertrophic scar formation].
Kuang F, Zhang Z, Chen B, Liu CL, Zhao YY, Xu ZR, Li XJ. Kuang F, et al. Zhonghua Shao Shang Za Zhi. 2017 Oct 20;33(10):634-638. doi: 10.3760/cma.j.issn.1009-2587.2017.10.011. Zhonghua Shao Shang Za Zhi. 2017. PMID: 29056026 Chinese.
Methods: Eight patients with hypertrophic scar after burn in need of surgery were admitted in our unit from January to October 2013, and then hypertrophic scar tissue and normal skin tissue of full-thickness skin donor site resected by surgery of the patients were c …
Methods: Eight patients with hypertrophic scar after burn in need of surgery were admitted in our unit from January to October 2013, and the …
Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma.
Aarntzen EH, Bol K, Schreibelt G, Jacobs JF, Lesterhuis WJ, Van Rossum MM, Adema GJ, Figdor CG, Punt CJ, De Vries IJ. Aarntzen EH, et al. Cancer Res. 2012 Dec 1;72(23):6102-10. doi: 10.1158/0008-5472.CAN-12-2479. Epub 2012 Sep 24. Cancer Res. 2012. PMID: 23010076
To show its utility, we conducted a retrospective study of a large cohort of metastatic melanoma patients (n = 91) enrolled in dendritic cell (DC)-based vaccination protocols to examine a hypothesized correlation of posttreatment skin-infiltrating lymphocytes (SKIL) …
To show its utility, we conducted a retrospective study of a large cohort of metastatic melanoma patients (n = 91) enrolled in dendritic cel …
SnoN functions as a tumour suppressor by inducing premature senescence.
Pan D, Zhu Q, Luo K. Pan D, et al. EMBO J. 2009 Nov 18;28(22):3500-13. doi: 10.1038/emboj.2009.250. Epub 2009 Sep 10. EMBO J. 2009. PMID: 19745809 Free PMC article.
Furthermore, overexpression of SnoN inhibits oncogenic transformation induced by Ras and Myc in vitro and significantly blocks papilloma development in vivo in a carcinogen-induced skin tumourigenesis model. The few papillomas that were developed displayed high levels of s …
Furthermore, overexpression of SnoN inhibits oncogenic transformation induced by Ras and Myc in vitro and significantly blocks papilloma dev …
17 results